In vitro transformation of mouse embryo cells by SV 40 DNA
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چکیده
منابع مشابه
Transformation of rat embryo cells in vitro by chemical carcinogens.
The in vitro transformation of mouse and hamster cells by chemical carcinogens has been described and well established. (1—5, 8, 13, 19, 20). Most in vitro transformations of cell cultures by chemical carcinogens yielded sarcomas upon reinsertion into syngeneic hosts. Transformation of rat embryo cells by 4-nitroquinoline 1-oxide (15) and fluorenylhydroxamic acids (7) has been reported recent...
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In vitro cell transformation of human embryonic cells could be induced by DNA extracted from virions of SV 40 purified by density gradient centrifugation. The result shows clearly that cell transformation is in· duced by incorporation ofa part of viral DNA into the genome. In addition, for the purpose of clarifing the biological differences between the normal and transformant, the alteration of...
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ژورنال
عنوان ژورنال: Okayama Igakkai Zasshi (Journal of Okayama Medical Association)
سال: 1971
ISSN: 0030-1558,1882-4528
DOI: 10.4044/joma1947.83.7-8_267